Search results for "Frontier Molecular Orbital Theory"

showing 2 items of 2 documents

N-benzoylindole-2,3-quinodimethane: Diels-Alder reactivity and synthetic applications for [b]annellated indoles

1991

Abstract The Diels-Alder reactivity of in situ generated N -benzoylindole-2,3-quinodimethane has been expanded considerably to include reactions with carbon- and hetero-dienophiles which furnish a variety of [ b ]annellated indoles as well as functionalized and annellated carbazoles. The frontier molecular orbital theory was found to be a useful model for the prediction of the experimental results under consideration of reactivity aspects.

ChemistryOrganic ChemistryDrug DiscoveryDiels alderOrganic chemistryFrontier molecular orbital theoryReactivity (chemistry)BiochemistryCycloadditionQuinoneTetrahedron
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New insights in chemical reactivity from quantum chemical topology.

2021

International audience; Based on the quantum chemical topology of the modified electron localization function ELFx, an efficient and robust mechanistic methodology designed to identify the favorable reaction pathway between two reactants is proposed. We first recall and reshape how the supermolecular interaction energy can be evaluated from only three distinct terms, namely the intermolecular coulomb energy, the intermolecular exchange‐correlation energy and the intramolecular energies of reactants. Thereafter, we show that the reactivity between the reactants is driven by the first‐order variation in the coulomb intermolecular energy defined in terms of the response to changes in the numbe…

Water dimerQuantum Chemical TopologyMaterials science010304 chemical physicsHydrogen bondIntermolecular forceGeneral ChemistryInteraction energy010402 general chemistryTopology01 natural scienceselectrophile0104 chemical sciencesComputational Mathematicselectron localization functionIntramolecular force0103 physical sciences[CHIM]Chemical SciencesMoleculeChemical ReactivityFrontier Molecular Orbital Theory[INFO]Computer Science [cs]Reactivity (chemistry)nucleophileTopology (chemistry)Journal of computational chemistryREFERENCES
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